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Research Interests- Chromosomal instability induced by human papillomavirus (HPV) oncoproteins
- DNA damage and repair in HPV oncoprotein expressing cells
- Effects of oncogenic kinase signaling on genome integrity
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Selected Publications- Duensing A, Spardy N, Chatterjee P, Zheng L, Parry J, Cuevas R, Korzeniewski N, Duensing S. (2009) "Centrosome overduplication, chromosomal instability, and human papillomavirus oncoproteins" Environ Mol Mutagen. in press | Abstract
- Spardy N, Duensing A, Hoskins EE, Wells SI, Duensing S. (2008) "HPV-16 E7 reveals a link between DNA replication stress, fanconi anemia D2 protein, and alternative lengthening of telomere-associated promyelocytic leukemia bodies" Cancer Res. 68:9954-63. | Abstract
- Hoskins EE, Morris TA, Higginbotham JM, Spardy N, Cha E, Kelly P, Williams DA, Wikenheiser-Brokamp KA, Duensing S, Wells SI. (2009) "Fanconi anemia deficiency stimulates HPV-associated hyperplastic growth in organotypic epithelial raft culture" Oncogene. 28:674-85. | Abstract
- Liu Y, Parry JA, Chin A, Duensing S, Duensing A. (2008) "Soluble histone H2AX is induced by DNA replication stress and sensitizes cells to undergo apoptosis" Mol Cancer. 7:61. | Abstract
- Duensing A, Chin A, Wang L, Kuan SF, Duensing S. (2008) "Analysis of centrosome overduplication in correlation to cell division errors in high-risk human papillomavirus (HPV)-associated anal neoplasms" Virology 372:157-64. | Abstract
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Other
Links
Duensing lab MGB Faculty Webpage
University of Pittsburgh |
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Stefan Duensing
| Office:
Hillman Cancer Center Suite 1.8 |
| Lab:Hillman Cancer Center Suite 1.7 |
| Phone:(412) 623-7719 |
| Fax:
(412) 623-7715
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duensing@pitt.edu
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Academic Affiliations- Member, Biochemistry and Molecular Genetics Graduate Program
- Assistant Professor
Dept. of Microbiology and Molecular Genetics
- Molecular Virology Program
University of Pittsburgh Cancer Institute
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Education- MD, University of Hannover Medical School, Germany, 1994
- Postdoctoral Fellow, Dept. of Pathology, Harvard Medical School, 1999
- Instructor in Pathology, Harvard Medical School, 2001
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