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Research Interests
  • Chromosomal instability induced by human papillomavirus (HPV) oncoproteins

  • DNA damage and repair in HPV oncoprotein expressing cells

  • Effects of oncogenic kinase signaling on genome integrity

 
Selected Publications
  1. Duensing A, Spardy N, Chatterjee P, Zheng L, Parry J, Cuevas R, Korzeniewski N, Duensing S. (2009) "Centrosome overduplication, chromosomal instability, and human papillomavirus oncoproteins" Environ Mol Mutagen. in press | Abstract

  2. Spardy N, Duensing A, Hoskins EE, Wells SI, Duensing S. (2008) "HPV-16 E7 reveals a link between DNA replication stress, fanconi anemia D2 protein, and alternative lengthening of telomere-associated promyelocytic leukemia bodies" Cancer Res. 68:9954-63. | Abstract

  3. Hoskins EE, Morris TA, Higginbotham JM, Spardy N, Cha E, Kelly P, Williams DA, Wikenheiser-Brokamp KA, Duensing S, Wells SI. (2009) "Fanconi anemia deficiency stimulates HPV-associated hyperplastic growth in organotypic epithelial raft culture" Oncogene. 28:674-85. | Abstract

  4. Liu Y, Parry JA, Chin A, Duensing S, Duensing A. (2008) "Soluble histone H2AX is induced by DNA replication stress and sensitizes cells to undergo apoptosis" Mol Cancer. 7:61. | Abstract

  5. Duensing A, Chin A, Wang L, Kuan SF, Duensing S. (2008) "Analysis of centrosome overduplication in correlation to cell division errors in high-risk human papillomavirus (HPV)-associated anal neoplasms" Virology 372:157-64. | Abstract

 
 
Other Links
Duensing lab
MGB Faculty Webpage
University of Pittsburgh
 
   
     
  Stefan Duensing
Office:  Hillman Cancer Center Suite 1.8
Lab:Hillman Cancer Center Suite 1.7
Phone:(412) 623-7719
Fax: (412) 623-7715
duensing@pitt.edu
 
Academic Affiliations
  • Member, Biochemistry and Molecular Genetics Graduate Program

  • Assistant Professor
    Dept. of Microbiology and Molecular Genetics

  • Molecular Virology Program
    University of Pittsburgh Cancer Institute

 
Education
  • MD, University of Hannover Medical School, Germany, 1994

  • Postdoctoral Fellow, Dept. of Pathology, Harvard Medical School, 1999

  • Instructor in Pathology, Harvard Medical School, 2001

 

 
 


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